Synthesis of Bicyclic Isoxazoles and Isoxazolines via Intramolecular Nitrile Oxide Cycloaddition.

نویسندگان

  • Wen-Chang Chen
  • Veerababurao Kavala
  • Yu-Hsuan Shih
  • Yu-Hsuan Wang
  • Chun-Wei Kuo
  • Tang-Hao Yang
  • Chia-Yu Huang
  • Hao-Hsiang Chiu
  • Ching-Fa Yao
چکیده

An efficient and straight forward procedure for the syntheses of bicyclic isoxazole/isoxazoline derivatives from the corresponding dimethyl-2-(2-nitro-1-aryl/alkyl)-2-(prop-2-yn-1yl)malonates or dimethyl 2-allyl-2-(2-nitro-1-aryl/alkyl ethyl)malonate is described. High yields and simple operations are important features of this methodology.

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عنوان ژورنال:
  • Molecules

دوره 20 6  شماره 

صفحات  -

تاریخ انتشار 2015